WiSE CRT System's unique approach
The WiSE CRT System uses proprietary wireless technology to pace the left ventricle endocardially and deliver personalized pacing therapy to patients. Offering a versatile and leadless design, the WiSE System brings a more physiologic approach for physicians to treat patients.
Pivotal SOLVE-CRT Trial Meets Endpoints
The SOLVE-CRT trial evaluated patients indicated for CRT who were previously untreatable or considered high risk upgrades. The study found that the WiSE CRT System, the only leadless left ventricular endocardial pacing (LVEP) device, can safely deliver CRT.
16.4%
improvement in left ventricular end systolic volume (LVESV) in heart failure patients in the first 6-months
80.9%
of patients had no serious device and procedure-related complications in the first 6-months
Empowering physicians, powering hearts
The WiSE CRT System is designed to overcome the limitations of conventional CRT and is the only leadless left ventricular endocardial pacing (LVEP) device.
Side view
How it works
The WiSE CRT System is designed to work with patients' existing implant to provide bi-ventricular pacing.
Co-implant
- Delivers conventional pacing
Battery
- Subcutaneous device ensures steady energy to the Transmitter
Transmitter
- Detects co-implant pacing pulses
- Within milliseconds, sends ultrasonic energy to power the Electrode
Electrode
- Converts ultrasonic energy into electrical pulses
- 0.05 cc leadless device features a polyester jacket for rapid endothelization (<45 days)
Leadless
Ultra-compact leadless device removes constraints of lead-based pacing systems
Versatile
Open platform coordinates therapy
with a range of existing pacing devices
LV Endocardial
More physiologic approach via left ventricular endocardial pacing (LVEP) for CRT
Procedure workflow
Three procedural stages occur to achieve optimal clinical outcomes:
1. Pre-assessment
Optimize location for ultrasound transmission to the left ventricle.
2. Surgical Implant
Surgically place Transmitter & Battery per pre-assessment optimization.
3. Electrode Mapping & Anchoring
Map left endocardial surface and implant Electrode with a single delivery system.
Current patents
The product(s) listed on this internet posting, either alone or in combination with other product(s), may be protected by one or more of the identified U.S. patents. Each product may also be protected by one or more patents issued outside of the U.S., and additional patent applications related to one or more of the listed products may be pending in the U.S. or elsewhere. The absence of a product name or patent number associated with any listed product does not constitute a waiver of EBR Systems’ intellectual property rights concerning that product or patent. This internet posting is intended to serve as notice under 35 U.S.C. § 287(a).
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