The WiCS^® Wireless Cardiac Stimulation technology was developed by EBR Systems to address the significant opportunity to eliminate cardiac pacing leads, historically a major source of complications and reliability issues.

Our initial product application focuses on the important underserved need in the heart failure population.  This population is underpenetrated by Cardiac Resynchronization Therapy (CRT), despite numerous clinical trials illustrating these therapies benefits.  Part of the reason for low penetration is the complexity of the procedure; the complications associated with coronary sinus leads used to pace the LV, and continued non-responder rates of approximately 30% despite advances in LV lead technology. 

CS leads are placed through the coronary sinus to access the cardiac venous structure on the epicardial surface of the heart.  WiCS approaches resynchronization therapy physiologically, recognizing that the site of stimulation has an impact on responder rates, and the physiologic benefit of endocardial vs. epicardial stimulation is significant.

The procedure is simple, resulting in predictable implant times.  Stimulating the endocardial surface eliminates a myriad of complications associated with CS leads:  acute and chronic lead dislodgement, CS dissection, acute and chronic phrenic nerve stimulation, and high pacing energy thresholds. 

The result is an elegant solution for a large number of heart failure patients indicated for CRT therapy: those patients implanted with an existing pacemaker or defibrillator and would benefit from upgrading their therapy, those patients denied therapy with failed attempts to implant a CS lead, and the large number of patients who are classified as non-responders or marginal responders. 

Our Mission

• Discover and investigate novel methods and underlying mechanisms for applying energy to stimulate human tissue;
• Apply our discoveries to meaningful medical products for cardiac stimulation to treat patients with cardiac arrhythmias, heart failure, or who are otherwise at risk from cardiac disease in order to improve and extend patients’ quality of life;
• Create an energetic and focused work environment that respects the diversity of its workforce and that adopts practices which gain the respect and commitment of its employees;
• Deliver safe and effective products and services to physicians and to patients with honesty and integrity.